Gene description for PDCD6IP
Gene name programmed cell death 6 interacting protein
Gene symbol PDCD6IP
Other names/aliases AIP1
ALIX
DRIP4
HP95
MCPH29
Species Homo sapiens
 Experiment description of studies that identified PDCD6IP in Liver cancer cells

1
Experiment ID1551
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVLarge EVs
Identification method Western blotting
PubMed ID 32082513   
OrganismHomo sapiens
Experiment descriptionHepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles
AuthorsJiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G.
Journal name J Extracell Vesicles
Publication year2020
SampleLiver cancer cells
Sample nameHuh-7 - 10K pellet
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

2
Experiment ID1552
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32082513   
OrganismHomo sapiens
Experiment descriptionHepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles
AuthorsJiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G.
Journal name J Extracell Vesicles
Publication year2020
SampleLiver cancer cells
Sample nameHuh-7 - 100K pellet
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

3
Experiment ID1553
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVLarge EVs
Identification method Western blotting
PubMed ID 32082513   
OrganismHomo sapiens
Experiment descriptionHepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles
AuthorsJiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G.
Journal name J Extracell Vesicles
Publication year2020
SampleLiver cancer cells
Sample nameHuh-7 - 10K pellet
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

4
Experiment ID1554
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32082513   
OrganismHomo sapiens
Experiment descriptionHepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles
AuthorsJiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G.
Journal name J Extracell Vesicles
Publication year2020
SampleLiver cancer cells
Sample nameHuh-7 - 100K pellet
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

5
Experiment ID1556
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32082513   
OrganismHomo sapiens
Experiment descriptionHepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles
AuthorsJiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G.
Journal name J Extracell Vesicles
Publication year2020
SampleLiver cancer cells
Sample nameHuh-7 - Fraction 7
Isolation/purification methodsCentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

6
Experiment ID1557
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32082513   
OrganismHomo sapiens
Experiment descriptionHepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles
AuthorsJiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G.
Journal name J Extracell Vesicles
Publication year2020
SampleLiver cancer cells
Sample nameHuh-7 - Fraction 8
Isolation/purification methodsCentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

7
Experiment ID1559
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32082513   
OrganismHomo sapiens
Experiment descriptionHepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles
AuthorsJiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G.
Journal name J Extracell Vesicles
Publication year2020
SampleLiver cancer cells
Sample nameHuh-7 - Fraction 6
Isolation/purification methodsCentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

8
Experiment ID1560
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32082513   
OrganismHomo sapiens
Experiment descriptionHepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles
AuthorsJiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G.
Journal name J Extracell Vesicles
Publication year2020
SampleLiver cancer cells
Sample nameHuh-7 - Fraction 7
Isolation/purification methodsCentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

9
Experiment ID1561
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32082513   
OrganismHomo sapiens
Experiment descriptionHepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles
AuthorsJiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G.
Journal name J Extracell Vesicles
Publication year2020
SampleLiver cancer cells
Sample nameHuh-7 - Fraction 8
Isolation/purification methodsCentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

10
Experiment ID1565
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32082513   
OrganismHomo sapiens
Experiment descriptionHepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles
AuthorsJiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G.
Journal name J Extracell Vesicles
Publication year2020
SampleLiver cancer cells
Sample nameHuh-7
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

11
Experiment ID2476
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34401050   
OrganismHomo sapiens
Experiment descriptionTPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis
AuthorsLiu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP.
Journal name J Extracell Vesicles
Publication year2021
SampleLiver cancer cells
Sample nameMHCC97L
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immuno-EM
Mass spectrometry
EV-TRACK -

12
Experiment ID2477
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34401050   
OrganismHomo sapiens
Experiment descriptionTPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis
AuthorsLiu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP.
Journal name J Extracell Vesicles
Publication year2021
SampleLiver cancer cells
Sample nameMHCC97L
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immuno-EM
Mass spectrometry
EV-TRACK -

13
Experiment ID2481
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34401050   
OrganismHomo sapiens
Experiment descriptionTPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis
AuthorsLiu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP.
Journal name J Extracell Vesicles
Publication year2021
SampleLiver cancer cells
Sample namePLC/PRF/5
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immuno-EM
EV-TRACK -

14
Experiment ID2482
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34401050   
OrganismHomo sapiens
Experiment descriptionTPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis
AuthorsLiu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP.
Journal name J Extracell Vesicles
Publication year2021
SampleLiver cancer cells
Sample namePLC/PRF/5 - clone 1
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immuno-EM
EV-TRACK -

15
Experiment ID2483
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34401050   
OrganismHomo sapiens
Experiment descriptionTPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis
AuthorsLiu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP.
Journal name J Extracell Vesicles
Publication year2021
SampleLiver cancer cells
Sample namePLC/PRF/5 - clone 2
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immuno-EM
EV-TRACK -

16
Experiment ID3088
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36631249   
OrganismHomo sapiens
Experiment descriptionS100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
AuthorsWang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO.
Journal name Gut
Publication year2023
SampleLiver cancer cells
Sample namePLC
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

17
Experiment ID3089
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36631249   
OrganismHomo sapiens
Experiment descriptionS100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
AuthorsWang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO.
Journal name Gut
Publication year2023
SampleLiver cancer cells
Sample namePLC
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

18
Experiment ID3090
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36631249   
OrganismHomo sapiens
Experiment descriptionS100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
AuthorsWang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO.
Journal name Gut
Publication year2023
SampleLiver cancer cells
Sample name97L
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

19
Experiment ID3091
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36631249   
OrganismHomo sapiens
Experiment descriptionS100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
AuthorsWang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO.
Journal name Gut
Publication year2023
SampleLiver cancer cells
Sample name97L
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

20
Experiment ID3092
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36631249   
OrganismHomo sapiens
Experiment descriptionS100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
AuthorsWang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO.
Journal name Gut
Publication year2023
SampleLiver cancer cells
Sample nameMIHA
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

21
Experiment ID3093
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36631249   
OrganismHomo sapiens
Experiment descriptionS100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
AuthorsWang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO.
Journal name Gut
Publication year2023
SampleLiver cancer cells
Sample nameMIHA
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

22
Experiment ID3094
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36631249   
OrganismHomo sapiens
Experiment descriptionS100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
AuthorsWang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO.
Journal name Gut
Publication year2023
SampleLiver cancer cells
Sample name97H
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

23
Experiment ID3095
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36631249   
OrganismHomo sapiens
Experiment descriptionS100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
AuthorsWang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO.
Journal name Gut
Publication year2023
SampleLiver cancer cells
Sample name97H
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

24
Experiment ID3098
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36631249   
OrganismHomo sapiens
Experiment descriptionS100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
AuthorsWang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO.
Journal name Gut
Publication year2023
SampleLiver cancer cells
Sample name97H
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

25
Experiment ID3099
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36631249   
OrganismHomo sapiens
Experiment descriptionS100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
AuthorsWang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO.
Journal name Gut
Publication year2023
SampleLiver cancer cells
Sample name97H
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

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